How industrialized food alters our microbiota and promotes chronic diseases

For millions of years, humans have coevolved with a complex gut microbiota, which plays a crucial role in their health and well-being. However, industrialization has led to radical changes in our lifestyle and diet, profoundly altering our gut microbiota. Numerous studies, including that of Li et al. (2025 ), have demonstrated that these microbiota disruptions are linked to an increase in chronic diseases, including cardiovascular disease, diabetes, and obesity.

1. The impact of industrialization on the intestinal microbiota

Industrialization has led to a drastic reduction in the diversity of the gut microbiota, a phenomenon observed in populations living in industrialized environments.

Several factors are responsible for this:

  • Processed and refined foods : Western diets high in refined sugars, saturated fats, and additives deprive the microbiota of the fiber essential for its balance.
  • Loss of beneficial microbes : Microbes that degrade fiber and regulate immunity are in sharp decline. In contrast, some pro-inflammatory bacteria, such as Bilophila, are on the rise.
  • Excessive use of antibiotics and cesarean sections : These practices disrupt the natural transmission of microbes from one generation to the next and alter the composition of the microbiota.

2. Consequences of industrialized microbiota on health

These changes have major repercussions on health:

  • A reduction in fiber fermentation leads to a decrease in short-chain fatty acids, which are essential for intestinal and metabolic health.
  • Enzyme depletion prevents proper assimilation of complex carbohydrates present in unprocessed foods.
  • An increase in pro-inflammatory bacteria promotes chronic diseases linked to inflammation.

3. Can we restore our microbiota?

In response to this situation, researchers are exploring strategies to restore a healthier microbiota. Li et al. (2025) conducted a clinical trial of a diet inspired by non-industrialized populations, combined with the administration of Limosilactobacillus reuteri , a bacterium absent from Western microbiotas but present in rural populations of Papua New Guinea.

The results are promising:

  • The diet corrected some alterations in the microbiota caused by industrialization.
  • It also favorably modified microbiota-derived blood metabolites involved in chronic diseases.
  • Finally, it generated significant cardiometabolic benefits, independent of L. reuteri administration.

Towards adapted dietary recommendations:

These findings reinforce the idea that nutrition plays a vital role in gut and overall health. Rather than attempting to recreate an ancestral microbiota, it seems more appropriate to promote a diet rich in fiber, legumes, fermented foods, and prebiotics.

4. Conclusion

Industrialization has disrupted our microbiota and fostered the emergence of chronic diseases. Restoring a healthy balance requires, above all, an appropriate diet, inspired by traditional diets rich in nutrients that support the microbiota. These advances pave the way for new nutritional and therapeutic strategies to preserve our long-term health.

That's why we created Daily Energy® . It's an innovative formulation, based on restoring a healthy microbiota . In Daily Energy ®, we have chosen soluble fibers with prebiotic properties, promoting the growth of beneficial intestinal bacteria.

  • Inulin is a natural component of chicory ( Cichorium intybus L. ), a plant known since ancient times. We have also selected Actilight®, a fructo-oligosaccharide (FOS) synthesized from beet sugar.
  • Actilight® is a true fiber powerhouse. One teaspoon of Actilight® is equivalent to the amount of fiber found in 10 bananas, 700g of rye, or 40 cloves of garlic.

Elevate your mornings by replacing your usual coffee with Daily Energy®, a coffee that benefits your microbiota and contribute to the prevention of your health.

Comment l'alimentation industrialisée modifie notre microbiote et favorise les maladies chroniques
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